Clinpath Laboratories was formed in 1985 by two pathologists, Dr Svante Orell and Dr Edward Chandraratnam, as a Fine Needle Aspiration Clinic located in North Adelaide.

Clinpath moved to larger premises in 1988 with the establishment of Histopathology and Cytology. Over the next twelve months pathology services were expanded to include the disciplines of Microbiology, Haematology, Clinical Chemistry and Transfusion.

In 1992 Clinpath was purchased by Douglass Laboratories (based in SA and NSW). The merger of the two practices proved highly successful as it brought together a core of experienced and committed staff and ensured financial stability. At the same time Douglass Laboratories was listed publicly and Sonic Healthcare was born. In 1995 Clinpath Laboratories purchased Path Lab and all pathology services were consolidated at the current main laboratory site in Kent Town.

The next decade saw Clinpath's expansion into the hospital environment with on site laboratories established in the Ashford and Wakefield Hospitals.  By 2009 Clinpath had five hospital laboratories operating in Ashford Hospital, Calvary Wakefield, Calvary North Adelaide, Western Hospital and St Andrew's Hospital in addition to the main testing facility at Kent Town.